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GAD-65/67 Polyclonal Antibody, 100ul Site-directed Mutagenesis The protein associates with hamartin

SKU: 10532439168

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GAD-65/67 Polyclonal Antibody, 100ul Site-directed Mutagenesis The protein associates with hamartinGAD1 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin dependent diabetes. Glutamate decarboxylase 1 is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin dependent diabetes. This gene may

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Description

The protein associates with hamartin in a cytosolic complex

an antiparallel six-helical bundle that mediates homotypic protein-protein interactions

It is highly similar to JIP-1

A pseudogene exists on chromosome 18

Diseases associated with MYF5 include skeletal muscle cancer and botryoid rhabdomyosarcoma

GAD-65/67 Polyclonal Antibody, 100ul Site-directed Mutagenesis The protein associates with hamartinGAD1 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin dependent diabetes. Glutamate decarboxylase 1 is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin dependent diabetes. This gene may

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