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PTP22 Polyclonal Antibody, 50ul Mechanical Pipette SHC1 encodes three main isoforms

SKU: 10112172344

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PTP22 Polyclonal Antibody, 50ul Mechanical Pipette SHC1 encodes three main isoformsPTPN22 encodes of member of the non receptor class 4 subfamily of the protein tyrosine phosphatase family. The protein tyrosine phosphatase, non receptor type 22 is a lymphoid specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1

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Description

SHC1 encodes three main isoforms that differ in activities and subcellular location

SRC and PKCzeta

NPTX1 is a member of the neuronal pentraxin gene family

NADH-cytochrome b5 reductase (CYB5R3) and MOSC2

The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID)

PTP22 Polyclonal Antibody, 50ul Mechanical Pipette SHC1 encodes three main isoformsPTPN22 encodes of member of the non receptor class 4 subfamily of the protein tyrosine phosphatase family. The protein tyrosine phosphatase, non receptor type 22 is a lymphoid specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1

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